DNA Damage Recognition

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DNA Damage Recognition
By


Publisher:  CRC
Number Of Pages:  872
Publication Date:  2005-09-19
Sales Rank:  1359827
ISBN / ASIN:  0824759613
EAN:  9780824759612
Binding:  Hardcover
Manufacturer:  CRC
Studio:  CRC
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Book Description:


Covering an array of topics, this authoritative work summarizes recent developments, while providing timely reviews on the molecular mechanisms employed by cells to distinguish between damaged and undamaged sites and stimulate the appropriate repair pathways. Richly illustrated, this guide discusses the theoretical aspects of DNA damage recognition, exploring those that are relevant for various regulatory responses, such as transcriptional regulation or checkpoint arrest. It also details key concepts in the recognition of bulky DNA base damage, reviews the excision repair of non-bulky base damage, covers short-patch repair and the recognition and repair of single- and double-strand breaks

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