Dipeptidyl Aminopeptidases: Basic Science and Clinical Applications

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Dipeptidyl Aminopeptidases: Basic Science and Clinical Applications (Advances in Experimental Medicine and Biology)
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Publisher:  Springer
Number Of Pages:  239
Publication Date:  2006-04-12
Sales Rank:  2249517
ISBN / ASIN:  0387290583
EAN:  9780387290584
Binding:  Hardcover
Manufacturer:  Springer
Studio:  Springer
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Book Description: )


Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses, and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. Leading experts in the field will contribute to this book, which will present a state-of-the-art view on these enzymes at a time when our understanding of their function is growing ever more rapidly and therapeutic options have become imminent. The sections of the book will focus on various topics including DP IV and related enzymes in: expression and function, metabolic disorders, immune mechanisms and immune disorders, neuronal diseases and cancer, and related drug development.