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Preoperative and intraoperative lymph node (LN) staging is of paramount importance for patients with non-small cell lung cancer. The Council of the European Society of Thoracic Surgery took the initiative to organize workshops on intraoperative and preoperative mediastinal LN staging
术前和术后淋巴结分期对于非小细胞肺癌至关重要。欧洲胸外科学会(ESTS)开始组织相关人员研讨术前和术后淋巴结分期。
This resulted in specific guidelines. Relevant peer-reviewed publications on these subjects, the experience of the participants, and the opinion of the European Society of Thor acic Surgery members contributing online were used to reach a consensus.
根据参与者的经验及ESTS成员的意见,结合一些相关的学术性论文,达成了一个专门的规范。
For primary staging, mediastinoscopy remains the gold standard for the superior mediastinal LNs. Invasive procedures can be omitted in patients with peripheral tumors and negative mediastinal and hilar nodes on positron emission tomography scan。
初始阶段,纵隔镜检查仍然可以作为上纵隔淋巴结分期的金标准。在周围性肺癌和纵隔、肺门淋巴结正常的病人中的分期可以用pet扫描,而避免用侵入性检查。
Positron emission tomography-positive mediastinal findings should always be cytohistologically confirmed. New minimally invasive techniques that provide cytohistological diagnosis became available。Their specificity is high, but the negative predictive value is low. If they yield negative results, an invasive surgical technique remains indicated。For restaging, invasive techniques providing cytohistological information are advisable
Pet提示为阳性结果的基本可以都能够被细胞学所证实。而能提供细胞学证据的一些新的微创技术也很实用。虽然他们的诊断特异性都很高,但对于阴性结果的预测却没有什么价值。如果能够判断阴性结果,微创技术在此方面就很有前景。侵入性操作技术能够为重新分期提供所需要的细胞学证据。
Systematic nodal dissection is recommended in all cases to ensure complete resection. Lobe-specific systematic nodal dissection is acceptable for peripheral squamous T1 tumors if hilar and interlobar nodes are negative on frozen section studies
全肺切除术都需要系统淋巴结清扫。如果周围性肺癌(鳞癌)T1冰冻切片证实没有发生肺门及叶间淋巴结侵犯,可施行局部肺叶系统淋巴结清扫(此处不清)
The report from the pathologist should describe the number of LNs removed and studied, the overall number of metastatic LNs in each station, and the status of the LN capsule. We hope that the adherence to these guidelines will standardize and improve preoperative and intraoperative LN staging and pathologic evaluation of non-small cell lung cancer.
病理科的报道应该包括淋巴结转移及转移到每站的所有数量,同时还需要描述是否侵及淋巴结包膜。我们希望我们所制定的指导规范能够使手术前和手术中淋巴结分期规范化,同时帮助提高非小细胞肺癌的病理诊断价值
术前和术后淋巴结分期对于非小细胞肺癌至关重要。欧洲胸外科学会(ESTS)开始组织相关人员研讨术前和术后淋巴结分期。根据参与者的经验及ESTS成员的意见,结合一些相关的学术性论文,达成了一个专门的规范。初始阶段,纵隔镜检查仍然可以作为上纵隔淋巴结分期的金标准。在周围性肺癌和纵隔、肺门淋巴结正常的病人中的分期可以用pet扫描,而避免用侵入性检查。Pet提示为阳性结果的基本可以都能够被细胞学所证实。而能提供细胞学证据的一些新的微创技术也很实用。虽然他们的诊断特异性都很高,但对于阴性结果的预测却没有什么价值。如果能够判断阴性结果,微创技术在此方面就很有前景。侵入性操作技术能够为重新分期提供所需要的细胞学证据。全肺切除术都需要系统淋巴结清扫。如果周围性肺癌(鳞癌)T1冰冻切片证实没有发生肺门及叶间淋巴结侵犯,可施行局部肺叶系统淋巴结清扫(此处翻译不好)
病理科的报道应该包括淋巴结转移及转移到每站的所有数量,同时还需要描述是否侵及淋巴结包膜。我们希望我们所制定的指导规范能够使手术前和手术中淋巴结分期规范化,同时帮助提高非小细胞肺癌的病理诊断价值 |
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