No Link Between Abortion, Miscarriage and Breast Cancer

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No Link Between Abortion, Miscarriage and Breast Cancer
堕胎、流产和乳腺癌之间没有关联

04.23.07, 12:00 AM ET
美国东部时间2007年4月23日，上午12：00

MONDAY, April 23 (HealthDay News) -- Neither induced abortion nor miscarriage appears to influence breast cancer risk in premenopausal women, a new U.S. study concludes.
周一，4月23日(每日健康新闻)--堕胎和流产似乎都不会影响绝经前妇女的乳腺癌患病风险。美国的一项新研究总结道。

\"In this cohort study of young women, we found no association between induced abortion and breast cancer incidence and a suggestion of an inverse association between spontaneous abortion (miscarriage) and breast cancer incidence during 10 years of follow-up,\" says a team from Brigham and Women's Hospital, Harvard Medical School and the Harvard School of Public Health, Boston.
“在这项关于年轻妇女的群组研究中, 我们发现在人工流产与乳腺癌发病率之间不存在关联，同时发现了自然堕胎（流产）与其后10年的乳腺癌的发病率之间有逆相关的迹象。”一个来自波士顿布里格姆妇女医院（Brigham and Women's Hospital）、哈佛医学院和哈佛公共卫生学院的研究小组声称。

They reported their findings in the April 23 issue of the Archives of Internal Medicine.
他们的研究发现发表于4月23日的《美国内科杂志》(Archives of Internal Medicin)上。

The researchers examined data on almost 106,000 women who took part in the Nurses' Health Study II, which began in 1993. The women were ages 29 to 46 at the start of the study.
研究人员研究了参加护士健康研究II计划（Nurses' Health Study II）的几乎106,000位妇女的数据。此计划开始于1993年，当时参与此计划的妇女们的年龄在29到46岁之间。

Among the women, more than 16,000 reported having had an induced abortion at some point in their lives and almost 22,000 reported having had a miscarriage. Between 1993 and 2003, there were 1,458 new cases of breast cancer diagnosed among the women.
在这些女性中，超过16000位在她们生命的某个时候都有过人工流产史，将近22000位有过一次流产。从1993年至2003年,这些女性中共有1458例新发确诊乳腺癌病例。

They found no link between abortion, miscarriage and breast cancer generally. However, \"we observed associations in two subgroups, an association between induced abortion and progesterone receptor-negative breast cancer (cancer that does not respond to the hormone progesterone) and an inverse association between spontaneous abortion before the age of 20 years and breast cancer incidence.\"
他们并没有发现堕胎、流产与乳腺癌普遍关联。但是，“我们在两个分组中观察到了某种关联，一个出现在人工流产和孕激素受体阴性乳腺癌(一种对激素黄体酮无应答的癌症)之间；另一个是逆相关，存在于20岁之前的自然流产与乳腺癌的发病率之间。”
The researchers noted that these secondary analyses were based on small numbers of women, however. \"No obvious mechanisms can be provided for these subgroup findings; thus, chance has to be considered as a possible explanation,\" they wrote.

研究者指出，这些再评价是基于少量妇女。然而，“没有明显的机制可以解释这些小组的发现结果，因此，这些发现就有了被作为可能性解释的机会。。”他们写道。